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Chinese scientists map silkworm genomes

A graph from the thesis titled “High-resolution silkworm pan genome provides genetic insights into artificial selection and ecological adaptation”.

Following in the footsteps of the Human Genome Project launched in 1990 and the Rice Genome Project in 1998, another genome research project – this one conducted by Chinese sericulture scientists – has made a breakthrough.

According to a press release from Southwest University on Oct. 9, the world’s first super pan genome map of a silkworm has been created by scientists in Chongqing.

The project, conducted at the university’s State Key Laboratory of Silkworm Genome Biology, will enable silkworm science to enter the information age.

On September 24, a dissertation titled “High-resolution silkworm pan-genome provides genetic insights into artificial selection and ecological adaptation” was published in Nature Communications, a peer-reviewed, open-access scientific journal from Nature Portfolio founded in 2010.

It publishes research in the natural sciences, including physics, chemistry, earth sciences, medicine and biology.

Dai Fangyin, a professor and director of the laboratory and chief scientist of the National Sericulture Industry Technology System, said he and his group spent four years in-depth sequencing of 1,078 silkworm samples before finally coming up with the world’s first super pan genome. came. Map.

Dai said the samples, including 205 local strains, 194 improved varieties, 632 samples from the genetic pool of domesticated silkworms (Bombyx. mori), and 47 wild silkworms (Bombyx. tangerine), cover all major silkworm regions along the Silk Road—more than 90 percent of the world’s representative silkworm resources.

A genome is the sum of all genetic materials of an organism while a pan genome refers to the sum of all genomic information in a species.

The silkworm genome map has the largest long-read pan genome sequencing of the world’s plants and animals, and is of the highest quality, according to Dai.

“This is the greatest achievement in global sericulture research in the last century,” said Xiang Zhonghuai, an academic from the Chinese Academy of Engineering and an expert in silkworm genetics and breeding.

Xiang said the superpan genome map of the silkworm will solve the breeding bottleneck and open a new era for functional genomics and molecular breeding.

Xiang noted that the silkworm, an important biological and genetic resource that supports important industrial and scientific research, has led to international resource competition.

In 2003, researchers at Southwest University released the world’s first silkworm genome framework. “It laid the groundwork for the newly released super pan genome map, which is a milestone for the 21st century Maritime Silk Road,” Xiang said.

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